A pill that can stave off Alzheimer’s Disease, Diabetes, Cardiac Problems, and even Aging ??
Red Wine- Key to the French Paradox?
It has been heralded as The Red Wine Cure and the explanation for “The French Paradox”- the fact that the French eat rich, fatty foods like cream, pastry and cheese, yet are healthier as they age. Resveratrol is the remarkable component of red wine that has been heralded as the scientific breakthrough of this century and featured by: FOX News, 60 Minutes and WebMD. The discovery of resveratrol, found in the skins of red grapes, holds so much promise that millions of dollars have been poured into grants to study the impact of resveratrol on Alzheimer’s Disease, Diabetes, Parkinson’s Disease and longevity. Scientific studies comparing mice taking high doses of resveratrol to mice not taking resveratrol show that the mice taking resveratrol run faster and live up to 30% longer- and there is solid evidence of reversal or staving off the neurological progression of aging, such as memory impairment. In 2003 a study by Dr. Kristoff Westaff and Dr. Sinclair of Harvard University discovered that resveratrol activates a survival gene that may slow or reverse the progression of neurological diseases of aging such as Alzheimer’s Disease and Diabetes, and may even extend the lifespan! Watch the video below and be amazed!
What if there was a prescription pill that could slow or reverse neurological diseases of aging that lead to memory loss and cognitive impairment? A pill that could reverse memory loss associated with diabetes, Alzheimer’s Disease, and even Senile Dementia? A pill that could even expand the lifespan?? Scientists think it may be on the horizon! They say that in a few years, eighty year olds may function like 50 year olds!
Pharmaceutical companies all over the world are scrambling to develop a prescription pill form of resveratrol. It is likely that a prescription form of resveratrol will be approved by the FDA and available to the public in prescription form within the next five years. The results of Dr. Sinclair’s study were astounding, showing that resveratrol activates a survival gene that is normally inactive, which expansive potential health benefits. Dr. Sinclair launched a Cambridge, Massachusetts pharmaceutical company, Sirtus, to continue research and to develop a prescription resveratrol pill. The extreme importance of the discovery of the impacts of Resveratrol, and the strong scientific outcomes evidencing the potential anti-aging and neurological disease fighting benefits, is evidenced by the fact that Dr. Sinclair’s small company, Sirtus, has been bought by the pharmaceutical giant Glaxo Smith Kline for three quarters of a billion dollars!
Scientists from leading universities and labs have received grant funding to study the possible benefits of resveratrol. They believe that resveratrol may:
stave off or slow the progression of Alzheimer’s Disease and cognitive impairment
protect against or even reverse cognitive impairment and dementia
protect against memory loss associated with neuro-degeneration and aging
protect against neurological diseases of aging such as Parkinsons and Senile Dementia
improve cardiovascular health in aging
boost immune system
increase the lifespan
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Even as scientists all over the world pursue studies of the impacts of Resveratrol (see the partial list of studies below) in a quest to develop a prescription formulation, over the counter nutritional supplement products are now available that contain Resveratrol.space
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– Buyer Beware: Not all Resveratrol products are formulated to high quality standards! We recommend a resveratrol product MADE IN THE USA. –
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Resveratrol Made in the USA!
To our knowledge, Neither 60 Minutes, Fox News Network, Web MD and the other news agencies nor Dr. Sinclair have endorsed any nonprescription resveratrol supplement brand. DaVinci® Laboratories of Vermont has been a leader in nutritional research and product development for over 36 years, selling exclusively to Health Care Practitioners and Compounding Pharmacies worldwide. Their research and development department is under the full time direction of a Ph.D. Nutritional Biochemist, and includes a staff of top-ranking professionals working to develop and produce some of the most significant products in the industry.
Purity and Potency
Integrity of Formulation
Adherence to label claims
RESVERATROL-50 by Davinci® Labs of Vermont is our choice for a dietary supplement of Resveratrol, a polyphenol that is a natural antioxidant found in grape skins and other plants. It contains 200 mg of Resveratrol (polygonum cuspidatum) Extract yielding Trans-Resveratrol 50mg. The suggested use is one vegetarian capsule, once or twice daily. Accordingly, one bottle will last 2-4 months. Click the picture to see a larger image of the product. Buy it Now in The Memory Store™. space space
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While FDA has not yet approved a prescription form of resveratrol, the tremendous anti-aging and disease fighting potential of resveratrol is being studied, and synopsis/results have been published in PubMed for the following, which are just a small sample of the numerous scientific studies and grant funded research currently underway on the gene activating processes of resveratrol:
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.This study finds that reservatrol mimics the effects of dietary restriction in lower organisms. Editors Note: Dietary restriction (restriction of calories) has been shown to lead to increased health and longevity. In other words, it may be possible to achieve the anti-aging benefits of dietary restriction without restricting calories!Consuming a diet supplemented with resveratrol reduced infection-related neuroinflammation and deficits in working memory in aged mice.
Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer’s disease. Neurochemistry International. 2009 Feb;54(2):111-8. Epub 2008 Nov 8. Karuppagounder SS, Pinto JT, Xu H, Chen HL, Beal MF, Gibson GE, of the Department of Neurology and Neurosciences, Weill Medical College of Cornell University, Burke Medical Research Institute. The researchers note that because the properties of resveratrol seem ideal for treating neurodegenerative diseases, they have tested its ability to diminish amyloid plaques in mice. According to the authors, “This study supports the notion that onset of neurodegenerative disease may be delayed or mitigated with use of dietary chemo-protective agents that protect against beta-amyloid plaque formation and oxidative stress.”
Red wine ingredient resveratrol protects from beta-amyloid neurotoxicity. Gerontology. 2003 Nov-Dec;49(6):380-3. Savaskan E, Olivieri G, Meier F, Seifritz E, Wirz-Justice A, Müller-Spahn F. Psychiatric Clinic, University of Basel, Basel, Switzerland. Considering that: 1) beta-Amyloid peptide (Abeta), a neutrotoxic substance, has been implicated in cell death that occurs in Alzheimer’s Disease, 2) Resveratrol, a natural polyphenol mainly found in red wine, has been shown to be cardioprotective and chemoprotective, and 3) a moderate wine intake correlates with a lower risk for Alzheimer disease (AD), the researchers studied the neuroprotective effect of resveratrol. The researchers found that Resveratrol maintains cell viability and effects and an antioxidant action by enhancing the scavenging of free radicals in cells, and concluded that red wine may be neuroprotective through the actions of resveratrol.
Resveratrol promotes clearance of Alzheimer’s disease amyloid-beta peptides. The Journal of Biological Chemistry. 2005 Nov 11;280(45):37377-82. Epub 2005 Sep 14. Marambaud P, Zhao H, Davies P. Litwin-Zucker Research Center for the Study of Alzheimer’s Disease and Memory Disorders. The findings of this study demonstrate anti-amyloidogenic activity of resveratrol and suggest that this natural compound has a therapeutic potential in Alzheimer’s disease.
Resveratrol–a boon for treating Alzheimer’s disease? Brain Research Reviews. 2006 Sep;52(2):316-26.Anekonda TS. Neurological Sciences Institute, Oregon Health and Science University. The researchers note that Resveratrol is known to protect against cardiovascular diseases and cancers, as well as to promote antiaging effects in numerous organisms, and that Resveratrol also modulates pathomechanisms of debilitating neurological disorders, such as strokes, ischemia, and Huntington’s disease. They note that recent studies on red wine bioactive compounds suggest that resveratrol modulates multiple mechanisms of the pathology of Alzheimer’s disease, and that reports indicate that mechanisms of both aging and Alzheimer’s disease can be modulated by both calorie restriction, a process which Reservatrol mimics. This study examines and discusses the role of resveratrol in modulating the Alzenheimer’s Disease pathomechanisms.
Therapeutic potential of resveratrol in Alzheimer’s disease. BMC Neuroscience. 2008 Dec 3;9 Suppl 2:S6.Vingtdeux V, Dreses-Werringloer U, Zhao H, Davies P, Marambaud P. Litwin-Zucker Research Center for the Study of Alzheimer’s Disease, The Feinstein Institute for Medical Research. The authors note that studies indicate that moderate consumption of red wine is associated with a lower incidence of dementia and Alzheimer’s disease, and that data have clearly demonstrated the neuroprotective properties of the naturally occurring polyphenol resveratrol with respect to stress and diseases. They discuss the fact that recent research in cell cultures and animal models has shed light on the molecular mechanisms potentially involved in the beneficial effects of resveratrol intake against the neurodegenerative process in Alzheimer’s disease.
The Oregon Alzheimer’s Disease Research Small Grants Program is funded by Oregon residents who donate portions of their state tax refunds toward Alzheimer’s disease research. One of the studies funded by the Oregon Alzheimer’s Disease Research Small Grants Program is that of Joseph Quinn, M.D., associate professor neurology,Oregon Health & Science University School of Medicine and Teri Wadsworth, Ph.D., OHSU research assistant professor of neurology. Quinn and Wadsworth are studying the antioxidant effects that different concentrations of resveratrol have on beta amyloid, the protein that clumps to form plaques that kill brain cells in Alzheimer’s Disease. It is thought that Resveratrol activates an enzyme that protects brain cells from amyloid-induced death.
The amount of money being poured into research into the potential health properties of Resveratrol is astounding- and a testament to the amazing nature of the scientific discoveries which have led to belief that in identifying the workings of resveratrol, science may have found a key physiological component of the aging and anti-aging processes that will lead to effective therapeutic treatments and cures for a host of neurodegenerative diseases, including Alzheimer’s Disease, Mild Cognitive Impairment and Dementia.
Some of the many donors sponsoring grants for research into the health properties of Resveratrol include:
American Heart Association
National Institutes of Health
The Oregon Alzheimer’s Disease Research Small Grants Program
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Scientists expect that a prescription version of Resveratrol will be available within five years to support protective mechanisms in the fight against Alzheimer’s Disease, and neurodegenerative diseases of aging that lead to memory loss. In the meantime, Resveratrol can be taken in the form of dietary supplements, which are available for purchase now in The Memory Store™.